Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
Yantiao Formula
- Development stage
- Preclinical
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Yantiao Formula (YTF) is a traditional Chinese medicine (TCM) multi-herb formulation used primarily for the treatment of sepsis and related inflammatory conditions. The formula typically includes peach kernel, mirabilite, Angelica sinensis, Radix Scrophulariae, raw rhubarb, Radix Paeoniae, Flos Lonicerae, Forsythia, and Ophiopogon japonicus. Preclinical studies demonstrate that YTF exerts anti-inflammatory effects by inhibiting the p38MAPK pathway and reducing pro-inflammatory cytokines such as TNF-α and IL-6. It also modulates macrophage polarization (shifting from M1 to M2 phenotype), thereby attenuating acute lung injury induced by sepsis. Network pharmacology analyses indicate that its mechanisms involve multiple targets and pathways related to inflammation regulation and immune response[1][5][7].
- Other names
- Yantiao FormulaYTF
02
Targets
IL-6 (Interleukin 6)MAPK14 (p38 mitogen-activated protein kinase alpha)TNFA (Tumor necrosis factor alpha (soluble))
Beyond the preview
Go deeper on Yantiao Formula.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Yantiao Formula.