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YDC101 is a small molecule drug candidate being developed by YD Global Life Science in collaboration with SapiensBio. The active ingredient in YDC101 is imatinib mesylate, a well-characterized tyrosine kinase inhibitor. YDC101 specifically targets the c-Kit receptor (also known as CD117 or Mast/stem cell growth factor receptor Kit), which plays a significant role in cellular signaling pathways related to vascular permeability and cell proliferation. The drug is currently in the preclinical lead optimization stage, with primary development focuses in ophthalmology—specifically for the treatment of diabetic macular edema (DME) and diabetic retinopathy (DR)—and potential applications in oncology.
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