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Yi-Shen Xiao-Zheng granules
- Development stage
- Preclinical
- Lead developer
- Beijing University of Chinese Medicine East Hospital
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Yi-Shen Xiao-Zheng granules is a traditional Chinese medicine (TCM) herbal formulation developed by Dongfang Hospital of Beijing University of Chinese Medicine. Formulated based on the TCM principles of tonifying the kidney and resolving stasis, it is designed to treat dysmenorrhea associated with pelvic endometriosis. Clinical studies, including randomized controlled trials, have evaluated its efficacy and safety in alleviating pain symptoms and modulating resting-state brain network connectivity (such as the insula functional network) in patients with endometriosis-induced dysmenorrhea.
- Other names
- Yi-Shen Xiao-Zheng granuleYishen Xiaozheng granuleYishen Xiaozheng granules益肾消癥颗粒
02
Targets
HIF1A (Hypoxia-inducible factor 1-alpha)HMOX1 (Heme oxygenase 1)IL-6 (Interleukin 6)
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