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Yigan Mingmu Oral Liquid
- Development stage
- Unknown
- Lead developer
- Guangxi Huibaoyuan Pharmaceutical Technology
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Yigan Mingmu Oral Liquid is a Traditional Chinese Medicine (TCM) formulation developed by Guangxi Huibaoyuan Pharmaceutical Technology Co., Ltd. for the treatment of alcoholic fatty liver disease (AFLD). It is specifically indicated for patients presenting with liver and kidney deficiency syndrome according to TCM diagnostic criteria. The therapy is designed to improve liver function and alleviate symptoms associated with fat accumulation in the liver due to chronic alcohol consumption. As of 2021, the drug was being evaluated in a Phase III randomized, double-blind, placebo-controlled clinical trial in China to assess its efficacy and safety profile in this patient population.
- Brand names
- Yigan Mingmu Oral Liquid
- Other names
- 益肝明目口服液
02
Targets
LC3 (Microtubule-associated proteins 1A/1B light chain 3B)TXNIP (Thioredoxin-interacting protein)AKT (RAC-alpha serine/threonine-protein kinase)MAPK3 (Mitogen-activated protein kinase 1)AQP4 (Aquaporin-4)
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