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Yigu Tang is a traditional Chinese herbal formula used primarily for bone health, particularly in the treatment of osteoporosis. It is designed to regulate bone metabolism and has been studied for its effects on miRNA related to bone turnover. The formula aims to strengthen bones by modulating biological pathways involved in bone remodeling and metabolism, making it beneficial especially for postmenopausal osteoporosis patients. It is a full-spectrum water-based herbal extract prepared according to traditional Chinese medicine principles. The exact mechanism involves regulation of miRNA participation in bone metabolism and modulation of macrophage colony-stimulating factor signaling pathways relevant to osteogenesis and resorption processes. This formula is used within the framework of TCM patterns related to kidney and spleen deficiency affecting bones.[3][7][8]
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