Drug intelligence / Profile preview

yinchengao decoction + ganlu detoxification pill

Development stage
Unknown
Lead developer
Wenzhou Haihe Pharmaceutical
Administration
Oral
01

Overview

Yinchengao Decoction + Ganlu Detoxification Pill is a combination therapy consisting of two classic Traditional Chinese Medicine (TCM) formulas: Yinchengao Decoction (Yinchen Hao Tang) and Ganlu Detoxification Pill (Ganlu Xiaodu Dan). Yinchengao Decoction is primarily used to clear damp-heat and alleviate jaundice, typically composed of *Artemisia scoparia*, *Gardenia jasminoides*, and *Rheum palmatum*. Ganlu Detoxification Pill is used to resolve dampness, clear heat, and detoxify, often applied in the treatment of seasonal febrile diseases and damp-heat syndromes. Together, this combination is frequently investigated in clinical practice for conditions characterized by severe damp-heat, such as acute icteric hepatitis, cholestasis, and certain viral infections like hand-foot-mouth disease. The mechanism involves anti-inflammatory, hepatoprotective, and choleretic effects, often mediated through the modulation of bile acid metabolism and the inhibition of inflammatory cytokines.

Other names
Yinchen Hao Tang + Ganlu Xiaodu DanYinchenhao Decoction + Ganlu Xiaodu PillYinchengao Decoction + Ganlu Xiaodu DanYinchen Hao Tang + Ganlu Xiaodu Pill
02

Targets

FXR (Farnesoid x-activated receptor)IL-6 (Interleukin 6)NF-κBTNFA (Tumor necrosis factor alpha (soluble))

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