Drug intelligence / Profile preview

Yinmajiedu Granules

Development stage
Phase 4
Lead developer
The First Affiliated Hospital of Zhengzhou University
Modality
Small Molecules
Administration
Oral
01

Overview

Yinmajiedu Granules is a Traditional Chinese Medicine (TCM) compound preparation developed by the First Affiliated Hospital of Zhengzhou University. It is primarily indicated for the treatment of acute respiratory distress syndrome (ARDS), particularly in cases associated with severe viral pneumonia such as COVID-19. The formulation is designed to clear heat, detoxify, and resolve phlegm, aiming to mitigate the systemic inflammatory response syndrome (SIRS) and the associated cytokine storm. By modulating immune activity and reducing the levels of pro-inflammatory mediators like interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α), the granules work to improve pulmonary function and enhance oxygenation indices in critically ill patients. The preparation typically consists of several herbal extracts, including *Lonicera japonica* and *Ephedra sinica*, which provide anti-inflammatory and immunomodulatory effects.

Brand names
Yinmajiedu Granules
Other names
Yinma Jiedu Keli银马解毒颗粒
02

Targets

IL1B (Interleukin-1 beta)IL-6 (Interleukin 6)TNFA (Tumor necrosis factor alpha (soluble))

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