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yinxieling
- Development stage
- Unknown
- Lead developer
- Guangdong Provincial Hospital of Traditional Chinese Medicine
- Administration
- Oral
01
Overview
Yinxieling is a Traditional Chinese Medicine (TCM) herbal formula developed and utilized by the Guangdong Provincial Hospital of Traditional Chinese Medicine for the treatment of psoriasis vulgaris. It is primarily indicated for patients exhibiting the blood-stasis or blood-heat syndromes according to TCM diagnostic criteria. The formula is composed of multiple herbal ingredients, including *Rehmannia glutinosa*, *Salvia miltiorrhiza*, and *Dictamnus dasycarpus*, which are thought to work synergistically to modulate the immune system, inhibit keratinocyte proliferation, and reduce systemic inflammation. Clinical research has focused on its ability to alter microRNA expression profiles and downregulate pro-inflammatory cytokines such as TNF-α, IL-17, and IL-23, which are central to the pathogenesis of psoriasis.
- Brand names
- Yinxieling tablets
- Other names
- Yinxieling GranulesYinxieling DecoctionYinxieling FormulaYXL
02
Targets
FUS (Fused in sarcoma)IL-23 (Interleukin-23)IL8 (C-X-C Motif Chemokine Ligand 8)PCNA (Proliferating cell nuclear antigen)TGFB1 (Transforming growth factor Beta-1 proprotein)TNFA (Tumor necrosis factor alpha (soluble))
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