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yiqi busshenxiao sanjie prescription
- Development stage
- Preclinical
- Lead developer
- Dongzhimen Hospital of Beijing University of Traditional Chinese Medicine
- Administration
- Oral
01
Overview
Yiqi Busshenxiao Sanjie prescription is a Traditional Chinese Medicine (TCM) herbal decoction developed by researchers at Dongzhimen Hospital, Beijing University of Chinese Medicine, for the treatment of chronic kidney disease (CKD). The formula's name is derived from its therapeutic principles in TCM: "Yiqi" (tonifying Qi), "Busshen" (tonifying the Kidney), and "Xiao Sanjie" (dissipating nodules or resolving stasis). In the clinical context of CKD, the prescription is intended to improve renal function and patient prognosis by addressing underlying deficiencies and pathological accumulations such as fibrosis. It is currently being evaluated in prospective and retrospective cohort studies, alongside animal models, to validate its efficacy and safety in adult CKD populations.
- Other names
- Yiqi Busshenxiao Sanjie prescriptionYiqi Busshen Xiao Sanjie decoctionYiqi Busshen Xiao Sanjie formula
02
Targets
MET (Mesenchymal-epithelial transition factor receptor)CCND1 (Cyclin D1)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)CDK4 (Cyclin-dependent kinase 4)EGFR T790M (Epidermal growth factor receptor T790M mutant)
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