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Yiqi Guben Wan
- Development stage
- Preclinical
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Yiqi Guben Wan is a traditional Chinese medicine (TCM) formulation that has been investigated for its therapeutic potential, particularly in allergic asthma. Research indicates that it alleviates airway inflammation and remodeling by suppressing the TLR4/NF-κB signaling pathway, leading to reduced expression of key inflammatory mediators. Additionally, it has been shown to improve mitochondrial dysfunction, which contributes to its overall therapeutic effects in respiratory conditions.
- Other names
- YiQi GuBen formulaYiQi GuBen capsuleYQGB益气固表丸模拟剂
02
Targets
TLR4 (Toll-like receptor 4)RELA (Nuclear Factor Kappa B Subunit p65)TRAF6TFAM (Mitochondrial transcription factor A)PPARGC1A (Peroxisome proliferator–activated receptor gamma coactivator 1-alpha)NFKBIA (NFKB inhibitor alpha)MYD88 (Myeloid differentiation primary response protein MyD88)
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