yiqi huayu bushen

Yiqi Huayu Bushen is a compound traditional Chinese herbal medicine (TCM) formulated as a granule. It is primarily investigated for the treatment of cervical spondylotic myelopathy and cervical syndrome, specifically addressing the TCM syndromes of Qi deficiency, blood stasis, and kidney deficiency. The recipe's mechanism involves delaying intervertebral disc degeneration by regulating the metabolism of the extracellular matrix (ECM). It promotes the expression of aggrecan and type II collagen while inhibiting the expression of type X collagen and matrix metalloproteinase-13 (MMP-13). Additionally, it upregulates tissue inhibitor of metalloproteinase-1 (TIMP-1), thereby restoring the balance between ECM synthesis and degradation. Research also suggests it may influence the immune, endocrine, and coagulation systems, including the regulation of serum estradiol levels and hemorheological parameters.

Other names

益气化瘀补肾颗粒Yiqi Huayu Bushen RecipeYiqi Huayu Bushen GranuleYHBR