Yiqi Huoxue Decoction

Yiqi Huoxue Decoction is a traditional Chinese medicine (TCM) formula based on the principle of "tonifying Qi and activating blood circulation" to treat conditions attributed to "Qi deficiency and blood stasis". [5] As a multi-herb decoction, its specific composition can vary, but core ingredients often include herbs like Astragalus (Huang Qi), Angelica (Dang Gui), and Salvia (Dan Shen). [1, 15] The provided clinical trial information and research articles indicate its investigation for a range of conditions, including preventing restenosis after percutaneous coronary intervention in coronary heart disease, treating diabetic nephropathy, and aiding recovery from cerebral infarction. [7, 12] Research suggests its mechanisms involve improving microcirculation, reducing inflammation, providing antioxidant effects, and regulating cellular processes like autophagy and apoptosis. [3, 5, 8] For instance, in diabetic nephropathy models, it has been shown to protect podocytes and ameliorate kidney damage by activating autophagy. [2, 3] In cardiovascular models, it improves cardiac function by inhibiting apoptosis and regulating calcium flux. [1, 15] One specific formulation mentioned in clinical trials is Qi-Shen Dan-Shao granules.

Brand names

Qi-Shen Dan-Shao granules

Other names

Yiqi Huoxue prescriptionYi-Qi Huo-Xue prescriptionYiqi Huoxue recipeYiqi Huoxue Tongluo DecoctionYiqi Huoxue Tongmai decoction益气活血方