Yiqi Huoxue Huashi Recipe

Yiqi Huoxue Huashi Recipe is a traditional Chinese medicine (TCM) multi-herbal formula designed to "tonify qi," "activate blood circulation," and "resolve phlegm/dampness." It is composed of three main herbal groups: - *Yiqi* (tonifying qi): codonopsis, astragalus, licorice - *Huoxue* (activating blood): safflower, peach kernel, chuanxiong - *Huatan/Huashi* (resolving phlegm/dampness): pinellia, orange peel, poria[2][5] The recipe has been studied for its anti-inflammatory and anti-fibrotic effects in diseases such as chronic obstructive pulmonary disease (COPD), liver fibrosis associated with chronic hepatitis B infection[2][3], and atherosclerosis[5]. Mechanistically, it downregulates inflammatory mediators like IL-6 and TNF-α in lung tissue[2], suppresses matrix metallopeptidase 9 (MMP-9) activity involved in inflammation and extracellular matrix degradation[2], inhibits the TGF-beta/Smad signaling pathway implicated in fibrosis[3], and reduces activation of the Yes-associated protein/transcriptional coactivator with PDZ-binding motif (YAP/TAZ) pathway linked to fibrogenesis[3]. Clinical studies suggest efficacy superior to prednisone for COPD models without steroid-related side effects. The formula is typically manufactured by TCM pharmaceutical companies.

Other names

Yiqi Huoxue Huatan RecipeYiqihuoxuehuatan DecoctionYQHX