Drug intelligence / Profile preview

yiqi huoxue powder

Development stage
Unknown
Lead developer
Guangdong Provincial Hospital of Traditional Chinese Medicine
Modality
Small Molecules
Administration
Oral
01

Overview

Yiqi huoxue powder is a Traditional Chinese Medicine (TCM) formulation developed by the Guangdong Provincial Hospital of Chinese Medicine for the treatment of sepsis and pneumonia. The formula is based on the TCM principle of replenishing Qi and activating blood circulation (Yiqi Huoxue) to address the systemic inflammatory response and microcirculatory dysfunction characteristic of critical illness. It typically contains a combination of herbs such as *Astragalus membranaceus* and *Salvia miltiorrhiza*. Pharmacologically, the powder works by downregulating pro-inflammatory cytokines, including tumor necrosis factor (TNF) and interleukin-6 (IL-6), and inhibiting the NF-kappaB signaling pathway. Clinical research at the developer's institution has focused on its ability to protect against sepsis-induced organ injury, particularly in the lungs and heart, and to improve overall patient prognosis in intensive care settings.

Other names
Yiqi Huoxue San益气活血散
02

Targets

TNFA (Tumor necrosis factor alpha (soluble))IL-6 (Interleukin 6)NF-κB

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