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Yiqi Huoxue Qushi Powder is an investigational Traditional Chinese Medicine (TCM) formulation, with a name that translates to "Benefit Qi, Invigorate Blood, and Expel Dampness Powder." It is being studied as an oral therapy for carotid atherosclerosis. [16] According to TCM principles, it addresses conditions arising from "Qi deficiency" and "blood stasis," which are believed to contribute to atherosclerosis. [4] Research on related "Yiqi Huoxue" formulations, such as the granule form, indicates that they can reduce atherosclerotic plaque progression, improve lipid profiles, and suppress inflammation by decreasing levels of cytokines like IL-6 and IL-1β. [4, 7] The mechanism of action is thought to be multi-targeted, involving the inhibition of the SRC/AKT signaling pathway, among others. [4, 7] These formulations are combinations of multiple herbs, with compositions varying but often including Astragali Radix (Huang Qi) and other botanicals to achieve their therapeutic effect.
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