Drug intelligence / Profile preview

Yiqi Huoxue Qushi Powder

Development stage
Preclinical
Lead developer
Chengdu University of TCM Affiliated Reproductive and Maternal and Child Hospital
Administration
Oral
01

Overview

Yiqi Huoxue Qushi Powder is an investigational Traditional Chinese Medicine (TCM) formulation, with a name that translates to "Benefit Qi, Invigorate Blood, and Expel Dampness Powder." It is being studied as an oral therapy for carotid atherosclerosis. [16] According to TCM principles, it addresses conditions arising from "Qi deficiency" and "blood stasis," which are believed to contribute to atherosclerosis. [4] Research on related "Yiqi Huoxue" formulations, such as the granule form, indicates that they can reduce atherosclerotic plaque progression, improve lipid profiles, and suppress inflammation by decreasing levels of cytokines like IL-6 and IL-1β. [4, 7] The mechanism of action is thought to be multi-targeted, involving the inhibition of the SRC/AKT signaling pathway, among others. [4, 7] These formulations are combinations of multiple herbs, with compositions varying but often including Astragali Radix (Huang Qi) and other botanicals to achieve their therapeutic effect.

Other names
益气活血祛湿散Yiqi Huoxue formulaYiqi Huoxue Qushi San
02

Targets

IL1B (Interleukin-1 beta)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)IL-6 (Interleukin 6)

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