Drug intelligence / Profile preview

Yiqi Kaimi Recipe

Development stage
Preclinical
Modality
Small Molecules
Administration
Oral
01

Overview

Yiqi Kaimi Recipe is a traditional Chinese medicine (TCM) herbal compound used primarily for the treatment of functional constipation. It is formulated from multiple herbs and has been shown in preclinical and clinical studies to promote gastrointestinal motility by increasing the contraction frequency and amplitude of colonic smooth muscle. Mechanistically, it modulates levels of substance P proteins and neuronal nitric oxide synthase (NOS1) in the enteric plexus, enhancing intestinal peristalsis[1][2][3][5]. The recipe is believed to act through regulation of protein phosphorylation pathways that affect gut motility[2]. It is typically used as part of integrative therapy for chronic or functional constipation.

Brand names
Yiqi Kaimi Recipe
Other names
Yiqi Kaimi prescriptionYi Qi Kai Mi Fang益气开秘方
02

Targets

SP (Substance P)NOS1 (nNOS)

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