Yiqi Yangyin Formula

Yiqi Yangyin Formula is a Traditional Chinese Medicine (TCM) herbal preparation specifically utilized for the treatment of **Primary Sjögren's Syndrome (pSS)**. Based on the TCM therapeutic principle of "supplementing Qi and nourishing Yin," the formula is designed to address the underlying "Qi and Yin deficiency" that characterizes the clinical presentation of dryness (xerostomia and keratoconjunctivitis sicca) and systemic fatigue. While the specific composition can vary between institutions, the formula used in clinical research (such as those led by **Guang'anmen Hospital**) typically includes herbs like *Radix Astragali* (Huangqi), *Radix Rehmanniae* (Shengdi), and *Radix Ophiopogonis* (Maidong). Mechanistically, it is thought to modulate the immune system by reducing the production of pro-inflammatory cytokines, regulating B-cell activity, and potentially protecting the secretory function of the salivary and lacrimal glands.

Other names

YiQi YangYin FormulaYi-Qi-Yang-YinYiqi Yangyin Decoction