Drug intelligence / Profile preview

Yiqi Yangyin Granule

Development stage
Preclinical
Modality
Implantable Devices → Device-based Delivery → Drug Delivery Systems, Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Inhalation Devices → Device-based Delivery → Drug Delivery Systems
Administration
Oral
01

Overview

Yiqi Yangyin Granule is a traditional Chinese medicine (TCM) herbal formulation. It is based on the TCM principles of "tonifying qi" and "nourishing yin." While there are several related formulations with similar names (such as Yiqi-Yangyin-Jiedu decoction, Yiqi Yangyin Huoxue granule, and others), specific information about a product named exactly "Yiqi Yangyin Granule" is limited in the literature. However, such formulas typically contain herbs like Astragalus root (Huangqi), ginseng, glossy privet fruit (Nuzhenzi), Eclipta alba, Chinese yam (Shanyao), and others[4][5]. These ingredients are believed to support immune function, improve hematopoiesis, reduce oxidative stress in bone marrow cells after injury or irradiation[5], and may have roles in metabolic regulation via pathways such as AMPK/SIRT/PGC-1α signaling[6]. The formula has been studied for its potential benefits in conditions like myelosuppression after radiation exposure[5], insulin resistance in diabetes models[6], and possibly as an adjunct therapy for cancer patients receiving EGFR-TKIs to delay drug resistance[1].

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