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yiqi yangyin jiedu fang
- Development stage
- Unknown
- Lead developer
- Beijing University of Chinese Medicine
- Administration
- Oral
01
Overview
Yiqi Yangyin Jiedu Fang is a Traditional Chinese Medicine (TCM) herbal formula designed to address the TCM pattern of 'Qi and Yin deficiency' accompanied by 'toxic heat.' It is primarily utilized as an adjuvant therapy in oncology, particularly for non-small cell lung cancer (NSCLC) and gastric cancer, to enhance the efficacy of conventional treatments like chemotherapy and targeted therapy while mitigating treatment-related side effects. The formula typically comprises a combination of herbs such as *Astragalus membranaceus* (Huangqi), *Panax quinquefolius* (Xiyangshen), *Ophiopogon japonicus* (Maidong), and *Hedyotis diffusa* (Baihuasheshecao). Its pharmacological mechanism involves multi-target actions, including immunomodulation, inhibition of tumor angiogenesis via the suppression of pro-angiogenic factors, and the induction of apoptosis in malignant cells through the activation of caspase pathways.
- Other names
- Yiqi Yangyin Jiedu DecoctionYQYYJDF益气养阴解毒方
02
Targets
VEGFA (Vascular endothelial growth factor A)CASP3 (Caspase-3)
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