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Yiqi Zhuyu Decoction (YZD) is a multi-component traditional Chinese medicine (TCM) herbal formulation used as an integrative therapy in oncology. It is primarily studied in combination with standard chemotherapy regimens, such as FOLFOX-4, for the treatment of metastatic colorectal cancer. The decoction is designed to replenish Qi and remove blood stasis (Yiqi Zhuyu) according to TCM principles, aiming to enhance the efficacy of chemotherapy while potentially mitigating side effects and improving patient survival outcomes. As a complex herbal mixture, it does not target a single biological molecule but rather exerts multi-target effects through its various phytochemical constituents.
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