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yiqihuayu decoction
- Development stage
- Phase 3
- Lead developer
- Ying Gao
- Administration
- Oral
01
Overview
Yiqihuayu Decoction is a Traditional Chinese Medicine (TCM) herbal formulation investigated for the treatment of acute ischemic stroke. The formula is based on the therapeutic principle of "Yiqi Huayu," which involves replenishing Qi and resolving blood stasis to restore neurological function and protect brain tissue from ischemic damage. It is typically composed of multiple botanical ingredients, including *Astragalus membranaceus*, *Salvia miltiorrhiza*, and *Ligusticum chuanxiong*, which are thought to exert neuroprotective effects through anti-inflammatory, antioxidant, and microcirculation-enhancing pathways. The PHYSIS trial (NCT04433403), led by researchers such as Ying Gao at Dongzhimen Hospital (Beijing University of Chinese Medicine), aims to characterize the specific pharmacodynamic substances within the decoction and evaluate its clinical efficacy in improving neurological outcomes during the acute phase of stroke.
- Other names
- Yiqihuayu DecotionYiqihuayu TangYiqihuayu FormulaYiqihuayu-Decoction
02
Targets
CASP3 (Caspase-3)IL-6 (Interleukin 6)TNFA (Tumor necrosis factor alpha (soluble))
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