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Yiqihuoxuetongqiaomingmu recipe (益气活血通窍明目方) is a Traditional Chinese Medicine (TCM) herbal formula primarily investigated for the treatment of non-arterial ischemic optic neuropathy (NAION). Developed by researchers at the First Affiliated Hospital of Guangzhou University of Chinese Medicine, the recipe is formulated to address the TCM patterns of Qi deficiency and blood stasis, which are believed to contribute to optic nerve ischemia. The formula typically consists of multiple botanical ingredients aimed at improving blood rheology, enhancing microcirculation in the optic disc, and exerting neuroprotective effects on retinal ganglion cells. In clinical settings, it is often evaluated as an adjuvant therapy to standard Western medical treatments, such as systemic corticosteroids, to improve visual acuity and visual field outcomes in patients with acute NAION.
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