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Yiqitongluo
- Development stage
- Unknown
- Lead developer
- Yunnan Provincial Hospital of Traditional Chinese Medicine
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Yiqitongluo is a Traditional Chinese Medicine (TCM) hospital preparation developed by the Yunnan Provincial Hospital of Traditional Chinese Medicine, specifically indicated for the treatment of diabetic peripheral neuropathy (DPN). The formula is based on the therapeutic principle of 'replenishing Qi and dredging collaterals' to address the underlying pathology of Qi deficiency and blood stasis common in diabetic patients. It typically consists of a complex mixture of herbal ingredients, including *Astragalus membranaceus* (Huangqi), *Pueraria lobata* (Gegen), and *Salvia miltiorrhiza* (Danshen). Pharmacologically, Yiqitongluo is designed to improve peripheral microcirculation, enhance nerve conduction velocity, and provide neuroprotection by reducing oxidative stress and inhibiting the polyol pathway and the formation of advanced glycation end-products (AGEs). It is primarily administered in granule or capsule form within the hospital's clinical practice.
- Brand names
- Yiqitongluo
- Other names
- Yiqitongluo GranulesYiqitongluo CapsuleYiqitongluo Formula益气通络颗粒益气通络胶囊
02
Targets
AR (Adrenergic receptors)AGER (RAGE)
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