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yiru tiaojing granule
- Development stage
- Unknown
- Lead developer
- Nanfang Hospital, Southern Medical University
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Yiru Tiaojing Granule is a Traditional Chinese Medicine (TCM) hospital preparation developed by the Nanfang Hospital of Southern Medical University for the treatment of hyperprolactinemia and its associated clinical manifestations, such as galactorrhea, amenorrhea, and infertility. The formulation is designed to soothe the liver, resolve phlegm, and activate blood circulation according to TCM principles. It typically comprises a complex mixture of herbal extracts, including *Prunella vulgaris*, *Salvia miltiorrhiza*, and *Cyperus rotundus*. Mechanistically, the granule is thought to regulate the hypothalamic-pituitary-ovarian axis, specifically by inhibiting the synthesis and secretion of prolactin from the anterior pituitary, potentially through dopaminergic pathways. It is often utilized as an alternative or adjunct to dopamine agonists like bromocriptine to improve patient tolerance and therapeutic efficacy.
- Brand names
- Yiru Tiaojing Granule
- Other names
- Yiru Tiaojing Keli溢乳调经颗粒
02
Targets
DRD2 (Dopamine D2 Receptor)PRLR (Prolactin receptor)
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