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Yirui
- Development stage
- Unknown
- Lead developer
- Infinitus
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Yirui is a dietary supplement developed by Infinitus (China) Company Ltd, specifically formulated to manage hyperlipidemia and support cardiovascular health. It is a combination of natural extracts, primarily Hawthorn (*Crataegus*) and *Gynostemma pentaphyllum*. The mechanism of action involves the synergistic effects of its herbal constituents: *Gynostemma pentaphyllum* contains gypenosides that activate AMP-activated protein kinase (AMPK), thereby regulating lipid metabolism and reducing fatty acid synthesis, while Hawthorn extracts provide antioxidant flavonoids that help inhibit lipid peroxidation and may modulate cholesterol synthesis pathways. In China, Yirui is registered as a health food (commonly referred to as a Blue Hat product) rather than a prescription pharmaceutical, intended for individuals seeking to regulate blood lipid levels and maintain vascular health.
- Brand names
- YiruiInfinitus Yirui Capsules
- Other names
- 无限极怡瑞胶囊
02
Targets
HMGCR (3-hydroxy-3-methylglutaryl-coenzyme A reductase)AMPK (Adenosine monophosphate–activated protein kinase)
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