Yishen Jietou decoction

Yishen Jietou decoction is a traditional Chinese medicine (TCM) herbal formula. It is used in clinical practice, particularly in China, for the management of chronic kidney disease and to delay the progression of chronic renal failure[2]. The formula is typically administered as a decoction—a water-based extract of multiple herbs—following TCM principles that emphasize multi-target, multi-pathway effects through synergistic action of its components. While specific ingredient lists for "Yishen Jietou decoction" are not detailed in the available sources, similar formulas such as Bupi Yishen Formula and other "Yishen" preparations often include herbs like Astragali Radix (Huangqi), Codonopsis Radix (Dangshen), Atractylodis Macrocephalae Rhizoma (Baizhu), Poria (Fuling), Dioscoreae Rhizoma (Shanyao), Polygoni Multiflori Radix Praeparata (Zhiheshouwu), Cuscutae Semen (Tusizi), Coicis Semen (Yiyiren), and Salviae Miltiorrhizae Radix Rhizoma (Danshen)[6]. The mechanism of action involves immunomodulation, anti-inflammatory effects, antioxidation, improvement of microcirculation, and protection against renal fibrosis. These actions are attributed to various bioactive compounds such as flavonoids, saponins, phenolic acids, alkaloids, triterpenes—many with demonstrated anti-inflammatory or nephroprotective properties[6]. Clinical studies suggest that this class of formulas can improve symptoms and slow disease progression when used alongside conventional therapies[2][6].

Other names

Yishen Jietou Tang