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Yishen Juanbi Decoction (YSJBD) is a Traditional Chinese Medicine (TCM) herbal formula specifically designed to treat "Bi-syndrome" (rheumatic conditions), with a focus on ankylosing spondylitis (AS). The formula is rooted in the principle of tonifying the kidney (Yishen) and dispelling wind, cold, and dampness to alleviate pain and stiffness (Juanbi). It typically contains a complex mixture of herbs such as *Rehmannia glutinosa*, *Dipsacus asper*, *Epimedium brevicornu*, and *Cibotium barometz*. Clinical evidence suggests that YSJBD reduces inflammatory markers, including serum immunoglobulins (IgA, IgG, IgM), and improves clinical outcomes such as the Visual Analog Scale (VAS) for pain and the Bath Ankylosing Spondylitis Functional Index (BASFI). It is often used in combination with modern nursing interventions to enhance patient quality of life and nutritional status.
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