Drug intelligence / Profile preview

yishen juanbi decoction

Development stage
Unknown
Lead developer
藥捷安康
Administration
Oral
01

Overview

Yishen Juanbi Decoction (YSJBD) is a Traditional Chinese Medicine (TCM) herbal formula specifically designed to treat "Bi-syndrome" (rheumatic conditions), with a focus on ankylosing spondylitis (AS). The formula is rooted in the principle of tonifying the kidney (Yishen) and dispelling wind, cold, and dampness to alleviate pain and stiffness (Juanbi). It typically contains a complex mixture of herbs such as *Rehmannia glutinosa*, *Dipsacus asper*, *Epimedium brevicornu*, and *Cibotium barometz*. Clinical evidence suggests that YSJBD reduces inflammatory markers, including serum immunoglobulins (IgA, IgG, IgM), and improves clinical outcomes such as the Visual Analog Scale (VAS) for pain and the Bath Ankylosing Spondylitis Functional Index (BASFI). It is often used in combination with modern nursing interventions to enhance patient quality of life and nutritional status.

Other names
Yishen Juanbi TangYSJBDYishen Juanbi
02

Targets

CASP3 (Caspase-3)TNFA (Tumor necrosis factor alpha (soluble))EFNB2 (Ephrin-B2)IL1B (Interleukin-1 beta)

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