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Yishen Pinggan Decoction is a traditional Chinese medicine (TCM) herbal formula used primarily for the treatment of hypertension and hypertensive renal damage. The formula is composed of multiple herbs designed to "nourish the kidney" and "calm the liver," in line with TCM theory. Pharmacological studies suggest that Yishen Pinggan Decoction exerts anti-inflammatory effects, reduces urine microalbumin levels, improves renal histology, and modulates inflammatory pathways such as NF-κB signaling. It has been shown to decrease pro-inflammatory cytokines including IL-1β, IL-6, and TNF-α in renal tissues. Its primary indications are hypertension-related kidney injury and possibly other forms of chronic kidney disease[7][9][1].
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