yishen-qingli-huoxue formula

Yishen-Qingli-Huoxue Formula (YQHF) is a Traditional Chinese Medicine herbal formula used for treating chronic kidney disease (CKD) and renal fibrosis. The formula works through multiple mechanisms including inhibiting indoxyl sulfate via the **AhR/snai1 signaling pathway**, reducing fibrotic factors such as smoc2 and cdh11, and antagonizing renal fibrosis. The formula has been validated through clinical randomized controlled trials and has demonstrated effectiveness in improving renal function, reducing proteinuria, and alleviating renal fibrosis in CKD patients[2][5][7]. The mechanisms involve anti-inflammatory effects, inhibition of epithelial-mesenchymal transition, and modulation of metabolic pathways related to uremic toxins.

Other names

YQHFYishen-Qingli-Huoxue FormulaYishenqinglihuoxue formula