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Yishen Shujin Decoction
- Development stage
- Unknown
- Lead developer
- Juan Jiao
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Yishen Shujin Decoction is a traditional Chinese medicine (TCM) herbal formula currently under clinical investigation for the treatment of fibromyalgia syndrome (FMS). Based on TCM principles, the formula is designed to "tonify the kidney" (Yishen) and "relax the tendons" (Shujin), addressing the chronic pain and musculoskeletal stiffness characteristic of fibromyalgia. The decoction is typically administered orally as granules. Clinical research, including randomized, double-blind, placebo-controlled trials led by investigators such as Juan Jiao, focuses on evaluating its efficacy in reducing pain intensity (measured by the Brief Pain Inventory) and improving overall health status and comorbidities. Mechanistic studies using brain structural and functional MRI are also being conducted to explore how the formula modulates central pain processing pathways.
- Other names
- Yishen Shujin DecoctionYishenShujin Decoction
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