Drug intelligence / Profile preview

Yishen Zhuyu Decoction

Development stage
Unknown
Administration
Oral
01

Overview

Yishen Zhuyu Decoction is a traditional Chinese medicine (TCM) herbal formula. It is composed of multiple herbs and used primarily in TCM practice for the treatment of conditions associated with "kidney deficiency" and "blood stasis," particularly in the context of male infertility and reproductive health. The decoction aims to tonify kidney function, invigorate blood circulation, and resolve stasis according to TCM theory. Clinical studies suggest it can improve semen quality parameters such as sperm concentration, motility, morphology, and overall reproductive symptoms in elderly men with infertility attributed to kidney deficiency and blood stasis patterns[1]. The precise mechanism of action from a biomedical perspective remains unclear due to its multi-component nature; however, it likely involves modulation of hormonal balance, improvement in microcirculation, anti-inflammatory effects, antioxidative stress reduction, or other pleiotropic actions typical for complex herbal formulas.

Other names
Yishen Zhuyu Tang
02

Targets

IL-6 (Interleukin 6)IL1B (Interleukin-1 beta)NLRP3 (Nod-like receptor family pyrin domain-containing protein 3)

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