Drug intelligence / Profile preview

Yishenzhongzifang

Development stage: Unknown
Lead developer: Beijing Hospital of Traditional Chinese Medicine
Administration: Oral

Overview

Yishenzhongzifang is a traditional Chinese medicine (TCM) herbal formula developed by the Beijing Hospital of Traditional Chinese Medicine (Clinical Medical College of Traditional Chinese Medicine, Capital Medical University). It is primarily indicated for the treatment of male reproductive disorders, specifically idiopathic asthenospermia and testicular injury. The formula is designed to address TCM patterns consistent with essence and blood deficiency (Shen-essence deficiency syndrome). Pharmacological studies suggest that Yishenzhongzifang exerts protective effects on spermatogenesis and testicular function by inhibiting oxidative stress, suppressing Caspase-3-mediated apoptosis, and regulating the Nrf2/GPX4/ACSL4 signaling pathway to inhibit ferroptosis in epididymal epithelial cells.

Other names: Yishen Zhongzi FangYishen Zhongzi PillYishenzhongzi formula益肾种子方

Targets

GPX4 (Glutathione peroxidase 4)NFE2L2 (Nuclear factor (erythroid-derived 2)-like 2)CASP3 (Caspase-3)

Beyond the preview

Go deeper on Yishenzhongzifang.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

Trial phase
Status
Readouts

Indications & development

Explore development by indication, patient population, and geography.

Indications
Development status
Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

Partners
Deal terms
Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

Patents
Expiration dates
Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

Competing assets
Targets
Development stage

Research & analysis

Connect source evidence and development news to your research questions.

Publications
News
Analysis

Bring the full picture into focus.

See how Gosset can support your research on Yishenzhongzifang.

Explore the full profile