Yixin Decoction

Yixin Decoction is a traditional Chinese medicine (TCM) herbal formulation used primarily for cardiovascular conditions, especially in the context of myocardial ischemia-reperfusion injury (MIRI). It is typically administered as a decocted mixture of multiple herbs, though the exact composition may vary by practitioner or region. Recent research highlights that polysaccharides from Shenxiong Yixin Decoction can reduce myocardial infarct size, improve cardiac function, and enhance cardiomyocyte survival following MIRI. The mechanism involves modulation of gut-derived exosomal microRNA-21 (miR-21), which is transported to the heart and helps inhibit oxidative stress and apoptosis in damaged myocardium by downregulating PDCD4 expression[1]. Clinical studies have also explored its use alongside conventional Western medicine for viral myocarditis in elderly patients[2].

Brand names

Yixin Decoction

Other names

Yinxin decoction