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Yixin Jiedu Formula is a Traditional Chinese Medicine (TCM) herbal prescription primarily investigated for the treatment of cardiovascular conditions, specifically heart failure with preserved ejection fraction (HFpEF). Developed and studied by institutions such as the Guangdong Provincial Hospital of Chinese Medicine, the formula is designed based on TCM principles to "tonify the heart and detoxify," addressing patterns of Qi deficiency and toxin accumulation. It typically consists of a combination of herbs known for their cardioprotective, anti-inflammatory, and anti-fibrotic properties. Clinical research, including trials registered in the Chinese Clinical Trial Registry (ChiCTR), aims to evaluate its efficacy in improving exercise tolerance, cardiac remodeling, and quality of life in patients with chronic heart failure.
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