Drug intelligence / Profile preview

yixin wan

Development stage
Unknown
Lead developer
Jiangxi Wannianqing Pharmaceutical
Modality
Small Molecules
Administration
Oral
01

Overview

Yixin Wan is a traditional Chinese medicine (TCM) pill developed and manufactured by Jiangxi Wannianqing Pharmaceutical. It is primarily indicated for the treatment of coronary heart disease and angina pectoris. The formulation typically contains a complex mixture of ingredients, including Ginseng, Artificial Musk, Bear Gall powder, Toad Venom (Chansu), Pearl, and Borneol. Its pharmacological actions are characterized by cardiotonic effects, increasing coronary blood flow, and improving myocardial oxygen supply. Specifically, the bufadienolides found in Toad Venom act as inhibitors of the sodium/potassium-transporting ATPase, thereby increasing myocardial contractility. Ginsenosides from Ginseng provide additional cardioprotective and anti-ischemic benefits. In TCM theory, it is used to tonify Qi, nourish the heart, and promote blood circulation to resolve stasis, addressing symptoms such as chest tightness, palpitations, and shortness of breath.

Brand names
Wannianqing
Other names
Yixin Pills益心丸
02

Targets

ATP1A (Sodium/potassium-transporting ATPase)

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