Drug intelligence / Profile preview

YMN101

Development stage
Phase 1
Lead developer
West China Hospital of Sichuan University
Modality
Cell Therapies, Vaccines & Immunotherapeutics
01

Overview

**YMN101** is an investigational, cell-based therapeutic cancer vaccine developed by West China Hospital for advanced solid tumors. It comprises irradiated tumor cells and stromal cells isolated from adjacent non-cancerous tissue or tumor tissue, administered with an unspecified adjuvant. Unlike several related YMN-series vaccines in the same study, YMN101 tumor cells are not transfected with granulocyte-macrophage colony-stimulating factor. The vaccine is intended to stimulate antitumor immunity against tumor-associated antigens and is being evaluated in a first-in-human Phase 1 study. ([clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07567222))

02

Targets

pMHC (Peptide-MHC complex family)

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