Drug intelligence / Profile preview

YMN107

Development stage
Phase 1
Lead developer
West China Hospital of Sichuan University
Modality
Cell Therapies, Vaccines & Immunotherapeutics
Administration
Subcutaneous
01

Overview

**YMN107** is an investigational, GM-CSF-transfected irradiated tumor-cell therapeutic cancer vaccine developed by West China Hospital. It is part of a platform of personalized cellular vaccines comprising irradiated tumor cells plus stromal cells isolated from adjacent non-cancerous tissue or tumor tissue and an unspecified adjuvant. The vaccine is intended to provide a broad repertoire of tumor-associated antigens while GM-CSF expression is intended to enhance antitumor immune priming. YMN107 is being evaluated as a subcutaneous first-in-human Phase 1 treatment for advanced malignant solid tumors. ([synapse.patsnap.com](https://synapse.patsnap.com/drug/11b9428af42f4fd7887ca9621331479f))

Other names
YMN 107YMN107YMN-107YMN107 tumor cell vaccineYMN-107 tumor cell vaccineYMN 107 tumor cell vaccine
02

Targets

CSF2R (Granulocyte-macrophage colony-stimulating factor receptor)

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