Drug intelligence / Profile preview

Yonsei Univ. College of Medicine RIPK3 compound 20

Development stage
Unknown
Lead developer
Yonsei University College of Medicine
01

Overview

Yonsei Univ. College of Medicine RIPK3 compound 20: sourced facts only. name: "Based on biochemical kinase assay results, 20 is comparable to GSK872 (2) with regard to activity against RIPK3 and less potent against RIPK1 than GSK872, indicating selectivity of 20 towards RIPK3 over RIPK1 is higher than that of GSK872." [PMID:37494773]; target: "Based on biochemical kinase assay results, 20 is comparable to GSK872 (2) with regard to activity against RIPK3 and less potent against RIPK1 than GSK872, indicating selectivity of 20 towards RIPK3 over RIPK1 is higher than that of GSK872." [PMID:37494773]; developer: "KU-KIST Graduate School of Converging Science and Technology, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul, 02841, Republic of Korea; Severance Biomedical Science Institute, Graduate School of Medicinal Science, Brain Korea 21 Project, Yonsei University College of Medicine, 50, Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea." [PMID:37494773]; stage: "Significantly, 20 could relieve the TNFα-induced systemic inflammatory response syndrome in vivo." [PMID:37494773]

02

Targets

RIPK3

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