Drug intelligence / Profile preview

YourVaccx

Development stage
Unknown
Lead developer
ImmunSYS
Modality
Vaccines & Immunotherapeutics
Administration
Intratumoral, Subcutaneous
01

Overview

YourVaccx is a breakthrough immunotherapy system developed by ImmunSYS for treating metastatic solid tumor cancers, particularly metastatic prostate cancer. The therapy employs a novel three-step approach: first, a segment of tumor undergoes controlled cellular lysis using the proprietary ANTIGENerator energy delivery device system, which liberates tumor antigens; second, a proprietary formulation of immunotherapeutic drugs (including checkpoint inhibitors like ipilimumab, pembrolizumab or nivolumab, and immune stimulants like sargramostim) is locally injected into the disrupted tumor; finally, this combination empowers the patient's immune system to create a personal in-situ autologous vaccine that attacks cancer throughout the entire body via an abscopal effect. Early clinical data has shown promising effectiveness in patients with metastatic prostate cancer and other difficult-to-treat advanced solid tumors.

Brand names
YourVaccx
02

Targets

CTLA-4 (Cytotoxic t-lymphocyte–associated protein 4)PDCD1 (Programmed cell death protein 1 receptor)

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