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YS-HBV-001 is a therapeutic and prophylactic vaccine candidate for Hepatitis B virus (HBV) infection, developed by LakeShore Biopharma (formerly Yisheng Biopharma). The vaccine utilizes the company's proprietary PIKA immunomodulating technology, which acts as a Toll-like receptor 3 (TLR3) agonist to enhance the immune response. It is designed to induce both humoral and cellular immunity against HBV. Clinical development has progressed to Phase 1 trials in Singapore, targeting both the prevention and treatment of chronic hepatitis B.
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