yttrium Y 90 carbon microspheres

Yttrium-90 carbon microspheres injection (NRT6003, TareSphere) is an innovative, carbon-based radioactive microsphere formulation developed by Chengdu New Radiomedicine Technology (NRT) for selective internal radiation therapy (SIRT) of solid tumors, primarily unresectable hepatocellular carcinoma (uHCC). The microspheres, measuring 20–45 μm in diameter, are delivered via minimally invasive intra-arterial infusion directly to the tumor's vascular network. Once lodged, the embedded yttrium-90 (Y-90) radionuclide decays, emitting high-energy, pure beta (β) radiation with a short half-life and a limited average tissue penetration range of approximately 2.5 mm. This localized radiation induces DNA damage and cytotoxic effects in cancer cells while minimizing collateral damage to surrounding healthy liver tissue.

Brand names

TareSphere

Other names

Y90 carbon microspheres NRT6003Y-90 carbon microspheres NRT6003Y 90 carbon microspheres NRT6003yttrium Y 90 carbon microspheres injectionyttrium-90 carbon microspheresyttrium90 carbon microspheresyttrium 90 carbon microspheresyttrium-90 carbon microspheres injectionyttrium90 carbon microspheres injectionyttrium 90 carbon microspheres injection