Drug intelligence / Profile preview

yu ping feng san jia jian

Development stage
Unknown
Administration
Oral
01

Overview

Yu Ping Feng San Jia Jian (玉屏风散加减) is a modified version of the traditional Chinese herbal formula Yu Ping Feng San (Jade Windscreen Powder). The base formula consists of three herbs—Astragalus root (Huang Qi), Atractylodes rhizome (Bai Zhu), and Saposhnikovia root (Fang Feng)—and is traditionally used to tonify Qi, strengthen the body's exterior defenses ("Wei Qi"), and reduce spontaneous sweating. The "Jia Jian" or "modified" designation indicates that additional herbs are included based on specific patient needs or clinical indications. These modifications often aim to enhance effects such as clearing heat, resolving phlegm, or addressing other symptoms alongside immune support. Mechanistically, Yu Ping Feng San Jia Jian works by modulating immune function and supporting the body's resistance to external pathogens according to Traditional Chinese Medicine theory. It is commonly used for conditions associated with recurrent respiratory infections, allergic diseases like urticaria and rhinitis, chronic fatigue due to Qi deficiency, spontaneous sweating from Wei Qi deficiency, and as adjunctive therapy in various immunodeficiency-related disorders[1][2][3][6][8].

Other names
玉屏风散加减Yu Ping Feng San Jia JianJade Windscreen Formula ModifiedYupingfengsan Jiawei
02

Targets

STAT1 (Signal transducer and activator of transcription protein 1)TSLP (Thymic stromal lymphopoietin)GST (Glutathione S-transferase alpha 3)

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