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**Yuleyin** is an orally administered traditional Chinese medicine herbal formula used as one component of an integrated psychosomatic intervention for subthreshold depression. In a multicenter randomized controlled trial, the intervention combined Yuleyin with group psychotherapy and Jue tune music therapy; the complete intervention was associated with sustained within-group improvements in depressive-symptom scores and was reported as feasible with good safety. The individual botanical constituents, molecular targets, manufacturer, and a defined pharmacologic mechanism for Yuleyin were not reported in the identified public publication.
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