Drug intelligence / Profile preview

Yuping Tongqiao Tablet

Development stage
Phase 3
Lead developer
Yiling Pharmaceutical
Modality
Small Molecules
Administration
Oral
01

Overview

Yuping Tongqiao Tablet is a traditional Chinese medicine (TCM) formulation developed for the treatment of persistent allergic rhinitis, particularly in patients diagnosed with "lung and spleen deficiency syndrome" according to TCM principles. The product is classified as a natural/herbal drug and has undergone multicenter, randomized, double-blind, placebo-controlled phase II and III clinical trials in China to evaluate its efficacy and safety for this indication. Its mechanism of action is based on TCM theory—aimed at strengthening lung and spleen function to alleviate symptoms such as sneezing, runny nose, nasal congestion, and itching. The specific molecular targets or pharmacological mechanisms are not detailed in available sources; the therapeutic effect is attributed to multi-component herbal synergy typical of TCM formulations[1][2][6].

Brand names
Yuping Tongqiao Tablet
Other names
玉屏通窍片
02

Targets

AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)IL8 (C-X-C Motif Chemokine Ligand 8)EGFR (Epidermal growth factor receptor)TLR4 (Toll-like receptor 4)VEGFA (Vascular endothelial growth factor A)IgE (Immunoglobulin E)IFNG (Interferon gamma)IL-4 (Interleukin 4)IL-5 (Interleukin 5)

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