Drug intelligence / Profile preview

Yushuda

Development stage
Unknown
Lead developer
Shanghai Mental Health Center
Modality
Small Molecules
Administration
Oral
01

Overview

Yushuda (郁舒达) is a Chinese patent medicine developed by the Shanghai Mental Health Center, specifically indicated for the treatment of major depressive disorder (MDD) and depressive syndromes. It is classified as a hospital preparation (hospital-made formulation) approved for clinical use within the Shanghai hospital system. Formulated as a granule, Yushuda is based on Traditional Chinese Medicine (TCM) principles, primarily aimed at soothing the liver and relieving qi stagnation. Pharmacological and clinical research conducted by the developer suggests that Yushuda exerts its antidepressant effects by upregulating the expression of brain-derived neurotrophic factor (BDNF) in the hippocampus and modulating the activity of monoamine neurotransmitter systems, including serotonin and dopamine. It is frequently utilized as either a monotherapy for mild-to-moderate depression or as an adjunctive treatment to improve the therapeutic response and reduce the side effects of conventional antidepressant medications.

Brand names
Yushuda
Other names
Yushuda granulesYushuda keli郁舒达Z05050141Z-05050141Z 05050141
02

Targets

5-HT (Serotonin receptors)BDNF (Brain-derived neurotrophic factor)DRD (Dopamine receptors)

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