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YZ-0121 is a preclinical **fixed-dose small-molecule combination** being developed by Guangdong Yinzhu Pharmaceutical Technology for **KRAS-positive non-small cell lung cancer**. The program is reported to target nuclear factor kappa B signaling and is listed in the developer's compound-formulation development platform; the individual active ingredients, formulation, route of administration, and precise pharmacologic effect on NF-κB have not been publicly disclosed.
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