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YZD-7082B is a novel, orally bioavailable selective estrogen receptor degrader (SERD). It has been developed as a potential therapeutic agent for the treatment of estrogen receptor-positive (ER+) breast cancer. The compound demonstrates high purity and enantiomeric excess, and its synthesis involves chiral resolution and advanced reduction techniques. As a SERD, YZD-7082B works by binding to the estrogen receptor and promoting its degradation, thereby inhibiting estrogen-driven tumor growth[1][10].
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