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Zag Bio neurology program

Development stage: Preclinical
Lead developer: Zag Bio
Modality: Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
Administration: Intravenous, Subcutaneous, Intraperitoneal

Overview

Zag Bio's neurology program is an undisclosed, preclinical-stage therapeutic candidate developed using the company's proprietary thymus-targeted bifunctional antibody platform. The drug is designed to deliver neural tissue-specific antigens directly to thymic antigen-presenting cells (APCs). This mechanism is intended to reestablish central T cell tolerance and promote the expansion of antigen-specific regulatory T cells (Tregs). The primary therapeutic objective is to halt immune-mediated nerve damage in autoimmune neurological diseases, with the ultimate goals of providing neuroprotection and facilitating remyelination.

Other names: Zag Bio neurology autoimmune disease programZag Bio thymus-targeted bifunctional antibody for neurology

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