Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
Zanthoxylum caribaeum extract
- Development stage
- Preclinical
- Lead developer
- Universidad Nacional de Colombia
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
*Zanthoxylum caribaeum* extract is a botanical extract derived from the Colombian plant *Zanthoxylum caribaeum* (Rutaceae family). It contains a mixture of phytosterols and carbazole-like compounds that act as Liver X Receptor (LXR) agonists. Developed primarily by researchers at the Universidad Nacional de Colombia, the extract is being investigated for its neuroprotective, anti-inflammatory, and remyelinating properties. In preclinical models of multiple sclerosis, Alzheimer's disease, and cerebral ischemia, the extract has demonstrated the ability to reduce demyelination, astrogliosis, and microgliosis, showing therapeutic potential for central nervous system disorders.
- Other names
- Zanthoxylum caribaeum Lam. extractZanthoxylum caribaeum leaf extractZanthoxylum caribaeum root extractZanthoxylum sp. extract
02
Targets
APOE (Apolipoprotein E)LSR (Lipolysis-stimulated lipoprotein receptor)NR1H3 (Liver X receptor beta)LXRB (Liver X receptor beta)
Beyond the preview
Go deeper on Zanthoxylum caribaeum extract.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Zanthoxylum caribaeum extract.