Drug intelligence / Profile preview

Zao Jiao Tong Luo

Development stage
Unknown
Lead developer
Shaanxi Momentum Pharmaceutical
Modality
Peptides, Small Molecules
Administration
Oral
01

Overview

Zao Jiao Tong Luo is a Traditional Chinese Medicine (TCM) formulation, most commonly encountered as Zao Jiao Tong Luo capsules, used primarily for the treatment of ischemic stroke and cerebral infarction. The preparation is designed to address the TCM patterns of "phlegm-stasis blocking the collaterals," aiming to improve neurological function and physical disability during the recovery phase of a stroke. Its pharmacological activity is attributed to a combination of herbal and animal-derived components, such as *Gleditsia sinensis* and *Hirudo* (leech). These ingredients work synergistically to inhibit platelet aggregation, promote fibrinolysis, and reduce blood viscosity, thereby improving cerebral microcirculation. Additionally, the formulation exhibits neuroprotective effects by modulating inflammatory pathways and reducing oxidative damage in brain tissues.

Brand names
Zao Jiao Tong Luo Jiao Nang
Other names
Zaojiao Tongluo
02

Targets

Fibrin (Factor Ia)F2 (Thrombin)

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